You may get a yeast infection during or after a course of antibiotics if the drugs affect beneficial bacteria in your vagina. Some practices and products may reduce the risk.

Antibiotics are used to kill off harmful bacteria in the body. But they can also destroy beneficial bacteria in the process, which may lead to a yeast infection.

Vaginal yeast infections are fungal infections of the vagina. They occur when a type of fungus called Candida, which is naturally present in the vagina, begins to grow out of control. Yeast infections can cause intense itching and irritation of the vagina and vulva — the outer part of the female genital area.

Read on to learn more about why this happens and how you can reduce your risk while taking antibiotics.

Vaginas maintain their own balanced mix of yeast and bacteria. A type of bacteria called Lactobacillus keeps the vagina slightly acidic, which isn’t welcoming to yeast. This slightly acidic environment keeps the yeast growing in the vagina under control.

Broad-spectrum antibiotics, which you might take for bronchitis or a sinus infection, are like a bomb to your body’s natural balance of bacteria. They wipe out the bad bacteria causing your illness.

Antibiotics also wipe out beneficial bacteria, including Lactobacillus. Without enough Lactobacillus, your vagina becomes less acidic, making it an ideal environment for yeast.

There are several things you can do to reduce your risk of getting a yeast infection after you take antibiotics.

Talk with your doctor

If you experience chronic yeast infections or tend to get a yeast infection every time you take antibiotics, tell your doctor. They may prescribe an oral antifungal pill called fluconazole (Diflucan) for you to take during your course of antibiotics.

You may be instructed to take one pill on the first day and another pill every seven days until you have finished the antibiotics. This should help to prevent an overgrowth of yeast while taking antibiotics.

Use an over-the-counter antifungal

Using an over-the-counter (OTC) antifungal cream or suppository can help prevent yeast infections caused by antibiotics. Antifungal agents can replace your good bacteria, helping to keep yeast in check.

Following the directions on the box, begin using your antifungal at the same time you start your antibiotics to prevent a yeast infection. You can also start using an antifungal at any point during your course of antibiotics.

Replenish your good bacteria

Antibiotics attack good bacteria all over your body. You may be able to undo some of this damage by increasing the number of good bacteria in your body.

Consider taking a probiotic supplement containing Lactobacillus. You can also try adding some yogurt containing live active cultures or fermented food to your diet.

Use yogurt (with or without honey) as a topical remedy

Some evidence suggests that topical use of yogurt, especially when combined with honey, may also help relieve symptoms of yeast infections.

For instance, a 2021 study found that a mixture of yogurt and honey was as effective as clotrimazole vaginal cream in reducing infection and more effective in relieving certain symptoms, such as itching and irritation.

If yogurt is used topically, it should be:

  • containing live, active cultures
  • plain and unflavored
  • free of added sugar or sweeteners

Don’t use antibiotics unnecessarily

Antibiotics can disrupt the balance of good bacteria in your body. When this balance is disrupted, yeast (Candida) can overgrow, increasing the risk of a yeast infection or exacerbating symptoms.

For illnesses that are not caused by bacteria (such as most colds, flu, or viral sore throats), antibiotics are not helpful. Ask your doctor whether antibiotics are truly necessary or if other treatments could be more effective.

If your doctor does prescribe antibiotics, take the full course exactly as directed. Stopping early can contribute to antibiotic resistance and may prevent the infection from being fully treated.

Other tips for prevention

Follow these tips to reduce your risk of developing a yeast infection, regardless of whether you’re taking antibiotics:

  • Change out of wet bathing suits and underwear as soon as possible. Yeast thrives in moist environments.
  • Avoid hot tubs and very hot baths. The only thing yeast loves more than a moist environment is a warm one.
  • Wear loose-fitting clothing. While there’s no clear link between tight clothing and yeast infections, tight pants can increase heat and moisture around your vulva.
  • Wear breathable, cotton underwear. Cotton underwear can help keep things cool and dry down there.
  • Never douche. Douching removes healthy bacteria.
  • Avoid vaginal deodorant products. This includes sprays, powders, and scented pads and tampons.
  • If you have diabetes, keep your blood sugar under control. High blood sugar levels encourage yeast growth.

If your yeast infection doesn’t improve after treatment, you should consult your doctor. OTC antifungal creams can take up to 14 days to treat a yeast infection.

You should make an appointment if you get recurrent yeast infections, which refers to having four or more yeast infections a year. These usually require prescription treatment because yogurt and other home remedies aren’t effective for this type of yeast infection.

If you’re still having symptoms after this point, you could have a different condition, such as bacterial vaginosis (BV). This is a bacterial infection with symptoms very similar to those of a yeast infection. But because it’s not caused by a fungus, it won’t respond to antifungal treatments.

Antibiotics can cause yeast infections in some people because they kill off beneficial bacteria that prevent the overgrowth of yeast in the vagina.

However, there are several things you can do to offset the negative effects of antibiotics and reduce your risk of developing a yeast infection.