Grapeseed oil is a popular topical treatment that may support healthy skin aging. There are different formats, such as extracts and liquids, but more research is needed to fully understand its benefits.

Grapeseed oil comes from the pressed seeds of grapes during the process of winemaking.

It’s commonly used in topical treatments because it’s rich in biological compounds that may have anti-inflammatory, antimicrobial, and antioxidant properties.

Keep reading to learn more about the possible benefits and risks of grapeseed oil for skin health, and how to use it.

Some research suggests that grapeseed oil may help support skin health and improve skin elasticity, suppleness, and strength.

According to research from 2025, grapeseed oil may do this by:

  • supporting skin barrier structure and effectiveness
  • preventing epidermal water loss and dry skin
  • boosting wound healing, cell restoration, and collagen production
  • preventing bacterial growth

A 2020 study also found that grapeseed oil is an effective natural ingredient for protecting the skin against UV rays and supporting healthy skin aging.

The potential benefits of grapeseeds for skin health are largely attributed to their rich polyphenol composition. Polyphenols are plant-based compounds that may have antioxidant properties.

Antioxidants can help protect the skin from oxidative stress, a process in which unstable molecules, known as free radicals, damage healthy skin cells. The antioxidant proanthocyanidin is particularly rich in grapeseed oil.

Polyphenols may also help reduce skin inflammation by blocking inflammatory pathways that can lead to skin swelling, discoloration, and dryness.

Grapeseed oil may play a role in managing skin conditions, such as eczema, psoriasis, acne, and skin cancer, while minimizing the potential side effects of other treatments.

However, more research is needed to fully understand the possible benefits of grapeseed oil for skin health.

Using grapeseed oil for your skin can be as simple or as labor-intensive as you’d like. It’s available in various forms, including gels, liquids, ointments, creams, and in its pure form.

Proponents of grapeseed oil often use its pure form as a serum on their face, applying it before bed. To achieve this, consider mixing a drop of grapeseed oil into a moisturizing face cream to help seal in moisture.

You can also mix grapeseed oil with other essential oils, such as frankincense or lavender. Add a few drops of another essential oil to an ounce of grapeseed oil for a mask and leave it on for 10 minutes.

You can also warm grapeseed oil slightly by placing a small amount in your palms and rubbing your hands together. Apply a generous amount to your skin as a moisturizing mask.

Grapeseed oil extract is available in both liquid and capsule forms, but oral intake may be less effective for skin health than topical applications.

Unless you’re allergic to grapeseed oil, there’s little risk to trying it out for your skin, according to the National Center for Complementary and Integrative Health.

That said, consider performing a skin patch test on a less visible part of your skin, such as your wrist or ankle, before applying grapeseed oil to your face. Wait 24 hours after the spot test to make sure you have no reaction to the oil and that your skin can tolerate it.

It’s also best to speak with a healthcare professional before using grapeseed oil, especially if:

  • you’re pregnant
  • you have a chronic skin condition, such as eczema and psoriasis
  • you’re taking medications

A healthcare professional, such as a primary care doctor, can help you determine whether it’s safe to apply grapeseed oil to your skin.

Yes, some research suggests that grapeseed oil may help increase collagen.

Anecdotal reports suggest that grapeseed oil doesn’t clog your pores. However, scientific studies are needed to support this.

Yes, you can use grapeseed oil on your face as part of your morning skin care routine.

Grapeseed oil is a simple, low risk, and relatively inexpensive treatment that may help support skin health by protecting it against oxidative stress, inflammation, and UV rays.

However, more studies are needed to fully understand its possible benefits and risks for skin health.

Before using grapeseed oil on your skin, speak with a healthcare professional. They can help you determine whether it’s safe for you and recommend an appropriate dosage.