Key takeaways

  • Headache wasn’t reported as a side effect in Zepbound’s studies. But, it may be a symptom of some of Zepbound’s side effects.
  • More common side effects of Zepbound are digestive side effects, such as diarrhea and constipation.
  • Many side effects of Zepbound may be temporary. Long-term side effects haven’t been reported with the drug at this time.

Zepbound is a prescription drug that’s used for weight loss and obstructive sleep apnea in certain adults.

It can cause side effects, such as nausea, diarrhea, and constipation. While headache isn’t a side effect of Zepbound, they can be a symptom of another side effect of the drug.

Learn more about what to do about headaches while using Zepbound and other side effects of the drug.

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Headache was not reported in Zepbound’s studies. But there are a few side effects of Zepbound that headache can be a symptom of, such as:

How to get rid of Zepbound headache

If you are experiencing headache while using Zepbound, be sure to talk with your doctor. If it is a symptom of another side effect, such as low blood sugar, they will recommend ways to help manage that side effect which should help improve the headache.

Some home remedies that can help you find relief from headache include:

  • staying hydrated
  • getting the right amount of rest
  • applying a cool compress
  • taking over-the-counter pain medications, such as acetaminophen (Tylenol)
  • drinking caffeinated tea or coffee

Be sure to talk with your doctor or pharmacist before taking any new medication, including over-the-counter medications or supplements.

Some people may experience mild to serious side effects during their treatment with Zepbound.

More common side effects of Zepbound are digestive side effects, such as:

  • nausea and vomiting
  • abdominal pain
  • diarrhea
  • indigestion (upset stomach)
  • constipation

If you have questions about side effects of Zepbound, talk with your doctor or pharmacist.

In most cases, side effects of Zepbound should be temporary and some may be easily managed. But if you have symptoms that are ongoing or bothersome, talk with your doctor. They can recommend ways to help manage the side effects or discuss other treatment options if needed.

Long-term side effects haven’t yet been reported in Zepbound’s studies.

While Zepbound doesn’t cause headache, it may be a symptom of some of the drug’s side effects. Getting enough sleep and drinking plenty of water are a few ways to help find relief from a headache.

If you experience a headache while using Zepbound, talk with your doctor. They can help determine the cause and recommend best next steps for treatment.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.