Key takeaways
- Doses of Rystiggo are given via infusions under the skin by a healthcare professional.
- Rystiggo dosing ranges from 420 milligrams (mg) to 840 mg per infusion, depending on your body weight.
- At the beginning of treatment, infusions are administered once per week for six consecutive weeks.
- After the initial 6-week treatment cycle, your doctor will evaluate your response to Rystiggo and determine whether additional treatment is needed.
Rystiggo (rozanolixizumab-noli) is a brand-name medicine that’s used to treat myasthenia gravis in some adults. It is a targeted biologic medication made from living cells.
Form
Rystiggo comes as a liquid solution for infusion under your skin by a healthcare professional.
Strengths
Rystiggo comes as a liquid solution in single-use vials. Each vial has a drug concentration of 140 milligrams of Rystiggo per millimeter of solution (140 mg/mL).
There are four different dose strengths based on the amount of Rystiggo in the single-use vial:
- 280 mg per 2 mL
- 420 mg per 3 mL
- 560 mg per 4 mL
- 840 mg per 6 mL
The following information describes the dosages of Rystiggo that are recommended by the drug manufacturer. Your doctor will determine the best dosage to fit your needs.
The typical Rystiggo dosage for adults with myasthenia gravis is based on the person’s body weight in kilograms (kg). For reference, one kg equals about 2.2 pounds (lb).
The following table shows the recommended dosing of Rystiggo per the drug’s prescribing information:
| Your weight | Rystiggo dose per infusion | Volume of infusion |
|---|---|---|
| less than 50 kg (110 lb) | 420 mg | 3 mL |
| 50 kg (110 lb) to less than 100 kg (220 lb) | 560 mg | 4 mL |
| 100 kg (220 lb) or more | 840 mg | 6 mL |
To start Rystiggo treatment, you will be given one infusion per week for 6 consecutive weeks.
After this treatment cycle, your doctor will evaluate how your body has responded to Rystiggo and determine if you need future treatment cycles.
If additional Rystiggo treatment is needed, a new treatment cycle typically will not be started sooner than 9 weeks from the start of the previous treatment cycle.
If you have questions about your Rystiggo dosage or dosing schedule, talk with your doctor.
Rystiggo comes as a liquid solution for infusion slowly under the skin. The infusion is given by a healthcare professional. You’ll receive the infusion under the skin of your lower abdomen (belly) through an infusion pump.
You’ll typically receive Rystiggo infusions at your doctor’s office, a clinic, or in the hospital. Each infusion takes about 10 to 20 minutes, depending on dosage. A healthcare professional will monitor you for about 15 minutes after each infusion.
If you have questions about how you’ll receive Rystiggo, talk with your doctor.
It depends. You’ll receive Rystiggo once weekly for 6 weeks when you begin treatment. Based on your condition and how you respond to the medication, your doctor may continue treatment with Rystiggo. Typically, they won’t start a new treatment cycle for at least 63 days after your last cycle.
If you have questions about how long you’re likely to receive Rystiggo treatment, talk with your doctor.
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