The prescribed dosage for Revlimid (lenalidomide) may depend on a person’s individual treatment plan. Factors like your medical history and whether you have had a stem cell transplant may affect your dosage of Revlimid.

Revlimid (lenalidomide) is a prescription medication used to treat certain types of cancer that affect blood cells. Revlimid comes as a capsule that you swallow. It’s usually taken once daily, but the dosing schedule varies depending on the condition that’s being treated and other factors.

Revlimid is used in adults to treat the following cancers in certain situations:

The active ingredient in Revlimid is lenalidomide. Revlimid belongs to a group of medications called immunomodulators. These drugs work by boosting the ability of your immune system to fight the cancer’s growth.

This article describes the dosages of Revlimid, including its form, strengths, and how to take the drug.

The dosage of Revlimid depends on the condition being treated. For most conditions, your doctor will give you a dosing schedule or cycle for you to follow while taking this medication. Notify your doctor right away if you experience any side effects that may prevent you from taking your medication.

Revlimid’s form

Revlimid comes as a capsule you take by mouth. You’ll swallow it whole with water.

Revlimid’s strengths

Revlimid is available in several strengths: 2.5 milligrams (mg), 5 mg, 10 mg, 15 mg, 20 mg, and 25 mg.

The following information describes the dosing schedules that are commonly used or recommended for Revlimid. But be sure to take the dosage your doctor prescribes for you. They may adjust your dosage over time to reach the right amount for you.

Dosage for multiple myeloma

The usual starting dose of Revlimid for multiple myeloma depends on whether or not you’ve had a stem cell transplant.

You have not had a stem cell transplant

If you haven’t had a stem cell transplant, the starting dose of Revlimid for multiple myeloma is 25 mg. You’ll take this dose once daily on days 1 to 21 of a 28-day cycle. You won’t take the drug on days 22 to 28 of the cycle. Once a cycle ends, you’ll start a new cycle. Your doctor will tell you how many cycles you should complete.

You’ll take Revlimid along with dexamethasone, a steroid medication.

You have had a stem cell transplant

If you’ve had a stem cell transplant, the starting dose of Revlimid for multiple myeloma is 10 mg once daily. You’ll take this dose every day of a 28-day cycle.

Once a cycle ends, you’ll start a new cycle. Your doctor will tell you how many cycles you should complete. They may adjust your dosage of Revlimid when you start a new cycle.

Dosage for mantle cell lymphoma

The usual dose of Revlimid for mantle cell lymphoma is 25 mg. You’ll take this dose once daily on days 1 to 21 of repeated 28-day cycles. You won’t take Revlimid on days 22 to 28 of the cycle.

Your doctor may adjust your dosage of Revlimid over time.

Dosage for myelodysplastic syndromes

The usual dosage of Revlimid for myelodysplastic syndromes is 10 mg daily.

Your doctor may adjust your dosage of Revlimid over time.

Dosage for follicular or marginal zone lymphoma

The usual dose of Revlimid for follicular or marginal zone lymphoma is 20 mg. You’ll take this dose once daily on days 1 to 21 of repeated 28-day cycles. You won’t take Revlimid on days 22 to 28 of the cycle.

Once the cycle ends, you’ll start a new cycle. Your doctor will tell you how many cycles you should complete, up to 12. They may adjust your dosage of Revlimid over time.

To treat these conditions, you’ll take Revlimid along with a medication called rituximab (Riabni, Rituxan, Ruxience, Truxima).

You should take Revlimid according to your doctor’s instructions.

Depending on the condition being treated, your doctor may give you a dosing schedule or cycle to follow while taking Revlimid. A typical dosing cycle is 28 days.

During this timeframe you’ll likely take a dose on days 1 to 21 and no dose on days 22 to 28. Once the cycle ends, you’ll start a new cycle. Your doctor will tell you how many cycles you should complete.

You should take your daily dose of Revlimid around the same time each day (according to your dosing cycle). Choose the time of day that’s easiest for you to remember to take it. You may take Revlimid with or without food.

You’ll swallow Revlimid capsules whole with water. You should not open, break, or chew the capsules.

You should not touch or handle Revlimid capsules any more than you have to. If powder from inside the capsules comes in contact with your skin, wash the area immediately with soap and water. If the powder gets into your eyes, nose, or mouth, rinse the area thoroughly with water.

How long can you take Revlimid?

Revlimid is typically a long-term treatment. For most conditions, your doctor will give you a dosing schedule or cycle to follow. Based on how your body responds to this drug, your doctor will tell you how many cycles to complete.

Your doctor will monitor how your body responds to Revlimid treatment using blood tests. If you develop certain side effects of Revlimid (such as decreased blood cell levels or severe skin reactions), your doctor may adjust your dosage. Or they may have you temporarily stop treatment and then restart it at a lower dosage.

If you have questions about how long you’re likely to take Revlimid, talk with your doctor.

What if I miss a dose of Revlimid?

You should take your dose of Revlimid at about the same time each day. If you miss a dose of Revlimid, take the missed dose as soon as possible, up to 12 hours after your usual time.

But if you miss your dose of Revlimid by 12 hours or more, skip that day’s dose. Then, the next day, you should take Revlimid at your usual time. Do not take two doses to make up for a missed dose.

If you need help remembering to take your dose of Revlimid on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

The dosage of Revlimid you’re prescribed may depend on several factors. These include:

  • the type and severity of the condition you’re using Revlimid to treat
  • how your body responds to the drug
  • any side effects you may experience
  • other conditions you may have

If you have renal failure or other kidney problems, your doctor will likely prescribe a lower dosage of Revlimid for you. Your doctor will adjust your dose depending on the severity of your kidney problems.

For more details about renal dosing adjustments for Revlimid, see the drug’s prescribing information.

Do not take more Revlimid than your doctor prescribes. Taking more than this can lead to serious side effects.

Symptoms of overdose

Symptoms caused by a Revlimid overdose can include:

What to do in case you take too much Revlimid

Call your doctor right away if you think you’ve taken too much Revlimid. You can also call 800-222-1222 to reach America’s Poison Centers, or use its online resource. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

Q:

Would a higher dosage increase my risk of side effects from Revlimid? What is the maximum daily dosage of this drug?

Anonymous

A:

Possibly. Your doctor will choose the dosage of Revlimid that’s right for you based on your specific condition. Other medical conditions you have can also affect your dosage.

If you develop certain side effects, your doctor may adjust your dosage. Or they may have you temporarily stop treatment and then restart it at a lower dosage.

The maximum daily dosage of Revlimid depends on the condition being treated. To learn more, see “What are the typical dosages of Revlimid?”.

If you have any questions about your dosage, talk with your doctor.

The Healthline Pharmacist TeamAnswers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.