Key takeaway

  • Zepbound is an injectable medication that is typically given once per week. If you are traveling, you will need to consider how many doses of the medication you will need to take with you.
  • It is typically stored in the refrigerator and can be kept cold during travels, but depending on the form may be kept out of the refrigerator for 21 or 30 days.
  • TSA regulations allow for medications to be in carry-on luggage.

If you are traveling with Zepbound, either in a car or on a plane, you may wonder how you can keep the medication cold and whether there are any restrictions to be aware of.

To help keep Zepbound at the right temperature while traveling, consider storing it in a thermal or insulated case or cooler. Zepbound is best stored in a refrigerator at a temperature between 36°F to 46°F (2°C to 8°C).

If you are traveling by airplane, you’ll want to keep Zepbound in carry-on luggage rather than checked luggage. This makes it easier to maintain the temperature of the medication.

You’ll want to avoid keeping Zepbound in the trunk or glove compartment, where the temperature may be too hot or cold, if you are traveling by car. If possible, you’ll also want to avoid leaving the medication in the car for long periods of time.

How long can Zepbound be out of the refrigerator?

Zepbound single-dose pen and single-dose vials can be kept out of the refrigerator, up to 86°F (30°C), for up to 21 days. If a single-dose pen or single-dose vial is stored at room temperature, do not be return it to the refrigerator.

Zepbound multi-dose vials or Kwikpens can be kept out of the refrigerator, up to 86°F (30°C), for up to 30 days.

Yes you can. You will want to keep Zepbound in carry-on luggage rather than checked luggage. This makes it easier to maintain the temperature of the medication.

The TSA allows injectable medications in carry-on luggage, but they need to go through standard security screening. It also allows necessary medications greater than 3.4 ounces (100 milliliters) in carry-on luggage.

You’ll need to declare any medication you have in your carry-on luggage at the checkpoint. You’ll also need to remove the drug from your bag for separate screening, along with any cooling packs.

Medical Perspective

In case of travel delays, should I bring more of my GLP-1 medication than I would normally use during my planned trip?

“Yes, I recommend packing at least one extra dose beyond what you expect to need. That way you are covered if your travel is delayed or a dose is misplaced.”

Olivia Taylor, PharmD, BCPS

Learn more about GLP-1 medications.

Quotes represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

It is best not to skip doses of your medications. Using Zepbound consistently helps ensure the drug works effectively.

It’s recommended that you give yourself Zepbound once per week, on the same day each week.

Talk with your doctor if you’re traveling and cannot or do not want to bring Zepbound with you. They can recommend strategies for maintaining weight loss and whether any dosing schedule changes need to occur.

Zepbound is an injectable medication that is stored in a refrigerator. When traveling with the medication, if possible you will also want to keep it cold.

Talk with your doctor or pharmacist if you have questions about traveling with Zepbound.

Disclaimer: While Healthline strives for factual, comprehensive, and current information, this article is not a substitute for a licensed healthcare professional’s expertise. Always consult a doctor before taking or discontinuing any medication. Drug information is subject to change and may not cover all uses, directions, precautions, warnings, interactions, reactions, or adverse effects. The lack of a warning does not guarantee a drug’s safety, effectiveness, or appropriateness for all patients or specific uses. Learn more about our approach to content integrity.